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New Discovery: Marine Algae Extract Could Help Treat Type 2 Diabetes

Researchers from SRM Institute of Science and Technology in Chennai, India, have found that an extract from a type of seaweed, Sargassum tenerrimum, might help treat type 2 diabetes. This seaweed extract, rich in compounds called phlorotannins, has shown promise in improving blood sugar levels and reducing damage caused by diabetes in a recent study on rats.

A New Hope for Diabetes Treatment

Type 2 diabetes is a widespread disease that affects how your body handles sugar (glucose). Many people with diabetes have to take multiple medications to manage their blood sugar levels, which can come with side effects. The researchers believe that natural compounds from seaweed could offer a new, more natural way to treat this condition.

How the Study Was Conducted

In the study, researchers fed rats a high-fat diet and gave them a small dose of a chemical called streptozotocin to induce diabetes, mimicking how type 2 diabetes develops in humans. They then treated these diabetic rats with the seaweed extract at two different doses or with metformin, a common diabetes medication, for three weeks.

Positive Results

The results were very encouraging:

  • The seaweed extract significantly lowered the rats’ fasting blood sugar levels and improved their insulin resistance.
  • It also helped normalize their cholesterol and liver enzyme levels.
  • The extract increased the levels of important antioxidant enzymes in the rats’ muscles, which protect against damage caused by high blood sugar.
  • Rats treated with the seaweed extract showed less damage to their pancreas (the organ that produces insulin) and liver.
  • The higher dose of the seaweed extract (400 mg/kg) was found to be more effective than the lower dose, showing a stronger improvement in all the measured parameters.

What This Means

Dr. Chitra Vellapandian, the lead researcher, explained the significance of the findings: “Our study shows that this seaweed extract can effectively reduce blood sugar levels, improve insulin resistance, and protect against damage caused by diabetes. This natural treatment could potentially offer a new way to manage type 2 diabetes with fewer side effects.”

Next Steps

While these findings are promising, more research is needed to understand exactly how the seaweed extract works and to test its safety and effectiveness in humans. The researchers are planning further studies to explore these questions.

This discovery opens up exciting possibilities for a natural and effective treatment for type 2 diabetes, potentially benefiting millions of people worldwide. Stay tuned for more updates as this research progresses.

For more information, you can contact Dr. Chitra Vellapandian at SRM College of Pharmacy, SRM Institute of Science and Technology, Chennai.

Source
Godlaveti Vijay NK, Vellapandian C. Ameliorative effects of phlorotannin-rich fraction of Sargassum tenerrimum in high-fat diet and low dose streptozotocin-induced metabolic changes and oxidative stress in diabetic rats. J Herbmed Pharmacol. 2023;12(3):367-379.

Narasimha Kumar GV

Dr. G. V. Narasimha Kumar currently working as a Scientist in the department of Pharmacology at Dr. Anjali Chatterji Regional Research Institute for Homeopathy under the CCRH, Ministry of Ayush, Govt. of India. He holds a PhD in Pharmacology from SRM University, Chennai, and a postgraduate degree in Pharmacology from Jawaharlal Nehru Technological University, Anantapur. Dr. Narasimha has previously served as a Research Assistant in the Department of Pharmacology at Siddha Central Research Institute, Chennai, and as an Assistant Professor at Sri Padmavathi School of Pharmacy, Tirupathi. An active contributor to his field, Dr. Narasimha has published 26 original research articles and 10 review articles in peer-reviewed journals, presented more than 15 papers at various conferences, and guided 10 postgraduate students in their research. He is a distinguished member of the Indian Pharmacological Society and serves as a CCSEA nominee for reputed organizations in Kolkata. Dr. Narasimha,s expertise lies in toxicity studies and the preclinical screening of test materials in non-communicable diseases, with notable proficiency in breeding small laboratory animals such as Wistar albino rats and BALB/c mice.

One Comment

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